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e time extrapolation used to determine Rin-exp. In addition to sag, the amplitude of the sagrelated rebound depolarization was also measured relative to the pre-stimulus membrane potential. Measurements of impedance were made as previously described. Briefly, oscillating subthreshold voltage responses were evoked by a sinusoidal current injection of constant amplitude of linearly increasing freque
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Ps have low toxicity and allow for feasible surface modifications to tune desirable charge and hydrophilicity properties. In addition, the use of the cationic polypeptide, PLL, is more biocompatible than PEI and can protect siRNA molecules from nucleases, which can be advantageous for cellular delivery and controlled release from the endosomal compartment. SNVs are examined as a potential therapy
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